What is Oxidative Stress?
Oxidative stress occurs when there is an imbalance between your body’s antioxidants and free radicals. Free radicals are oxygen-containing molecules with unpaired electrons, making them highly reactive. While free radicals play an essential role in certain bodily functions, such as fighting off pathogens, understanding antioxidants , excessive accumulation of free radicals can damage cells, potentially leading to various diseases.
Sources of free radicals include:
- Infections
- Excessive exercise
- Exposure to toxins
- Burn injuries
When free radicals accumulate in the body, they cause oxidative stress, leading to health issues such as:
- Chronic diseases
- Accelerated aging
- Inflammation
- Male infertility
What Causes Oxidative Stress?
Free radicals are naturally produced by the body in response to exercise or certain foods and drinks, foods and free radicals . For example, drinking alcohol increases free radicals in the body, alcohol and free radicals .
Additionally, many potential sources of free radicals exist in the environment, including:
- Cigarette smoke
- Air pollution
- Sunlight
- Industrial chemicals
- Radiation
- Pesticides
Long-term exposure to these sources can lead to oxidative stress and cause cell and tissue damage.

What Are the Risk Factors for Oxidative Stress?
Your environment and lifestyle choices can influence your likelihood of experiencing oxidative stress. The following factors may increase your risk of oxidative stress:
- Air pollution
- Smoking
- Sun exposure
- Excessive exercise
- Food contaminants like pesticides
- Alcohol consumption
- Exposure to industrial chemicals
- Radiation
- Medications
- Obesity
How Do You Know if You Have Oxidative Stress?
Some potential signs of oxidative stress include:
- Chronic fatigue ( chronic fatigue and oxidative stress )
- Memory loss ( memory loss and oxidative stress )
- Brain fog
- Infections
Oxidative stress can also contribute to visible signs of aging, such as gray hair and wrinkles. A small 2020 study found that participants who experienced premature graying had significantly higher oxidative stress levels than those who did not ( oxidative stress and gray hair ).
Lifestyle factors such as sun exposure and smoking can also cause skin damage.
Moreover, oxidative stress can increase your risk for chronic health issues like:
- Cancer: A 2021 study links smoking-related oxidative stress to tissue damage that can lead to cancer ( smoking and cancer ).
- Inflammatory diseases: Free radicals may also contribute to causing rheumatoid arthritis, a chronic inflammatory condition ( rheumatoid arthritis and oxidative stress ).
- Cardiovascular diseases: Evidence suggests that oxidative stress plays a role in heart disease and stroke.
- Neurological disorders: A 2017 review points out that oxidative damage plays a role in diseases like dementia and Alzheimer’s ( oxidative stress and neurological diseases ).
- Respiratory diseases: The same review also links lung diseases like asthma to oxidative stress ( respiratory diseases and oxidative stress ).
- Liver disease: Research from 2015 suggests that oxidative stress contributes to alcohol-induced liver injury ( oxidative stress and liver disease ).
- Kidney diseases: Oxidative stress can impair kidney function and potentially lead to kidney failure.

How Can I Prevent Oxidative Stress?
Since antioxidants neutralize free radicals, some experts believe that an antioxidant-rich diet is helpful in defending against oxidative stress. Key antioxidants include:
- Vitamins A, C, and E
- Beta-carotene
- Lycopene
- Selenium
- Zinc
- Phenolic compounds
The following foods are rich in these nutrients:
- Berries: Strawberries, raspberries, blueberries
- Leafy greens: Spinach, kale, cabbage
- Citrus fruits: Lemons, oranges, tangerines, grapefruits
- Bell peppers
- Tomatoes
- Pumpkin and squash
- Broccoli
- Sweet potatoes
- Grapes
- Avocados
- Cherries
- Nuts and seeds: Sunflower seeds, sesame seeds
- Seafood: Fish, oysters, shrimp
- Green tea
- Dark chocolate
Lifestyle Changes to Prevent Oxidative Stress:
- Quit smoking: Smoking increases your risk for a variety of diseases.
- Eat more antioxidant-rich foods: Opt for foods high in antioxidants, such as fresh berries and leafy greens, and limit saturated fat intake.
- Limit alcohol consumption: Research suggests that heavy alcohol consumption interferes with the body’s defenses against oxidative stress and can lead to various health problems, including liver disease ( alcohol and oxidative stress ).
- Reduce stress: If you’re chronically stressed, your body may have higher levels of oxidative stress. Find time to relax or start a meditation routine to reduce emotional stress.
- Protect your skin: While sunlight is an important source of vitamin D, sun exposure is also a cause of oxidative stress. Regularly wear sunscreen to protect your skin from sun damage.
- Get moving: Research indicates that moderate exercise is beneficial for preventing oxidative stress and improving overall health ( exercise and oxidative stress ). However, excessive exercise can actually increase oxidative stress.
- Get enough sleep: Sleep is essential for good health. The CDC links sleep deprivation to various health conditions, including type 2 diabetes, heart disease, and depression ( sleep and health ).
- Consider antioxidant supplements: Some research suggests that antioxidant supplements may provide benefits, including slowing the progression of osteoarthritis ( antioxidant supplements ). However, one 2019 study shows that some supplements can be toxic at high doses ( supplements and health ).
C60 is an example of a supplement that may offer antioxidant benefits. C60 Power’s Carbon 60 in Organic MCT Coconut Oil contains 99.99% pure sublimated carbon 60 (never exposed to solvents). It is formulated as a potent free radical scavenger to help protect the body from oxidative stress.
However, more research on the potential benefits and risks of supplements is needed. Consult your doctor to determine if supplements are right for you.
Conclusion
While your body needs some free radicals to function, excessive exposure through your environment and lifestyle choices can lead to oxidative stress, potentially causing damage and diseases. Ways to defend your body against oxidative stress include exercising, getting enough sleep, reducing stress, limiting alcohol consumption, quitting smoking, and eating a healthy diet rich in antioxidants.