Common Retinal Diseases: Symptoms, Diagnosis, and Treatments
常见的视网膜疾病及其症状、诊断和治疗方法
Retinal diseases are conditions that affect the function of the retina at the back of the eye. These diseases, which may result from genetic factors, aging, or external damage, are among the leading causes of vision loss. Common conditions include  age-related macular degeneration (AMD) ,  diabetic retinopathy ,  retinal tears ,  retinal detachment ,  macular holes , and  retinoblastoma . Additionally, there are genetic retinal diseases, such as  retinitis pigmentosa ,  Stargardt disease , and  Best disease . 

This guide explores the symptoms, diagnostic methods, and available treatments for these conditions.

What Are Retinal Diseases?

The  retina  is a light-sensitive layer at the back of the eye that converts light into electrical signals, which are sent to the brain via the optic nerve for processing. Any disease affecting retinal function can lead to vision impairment or loss. Retinal diseases include:

Retinal diseases are the  leading cause of blindness in low-income countries  and the second leading cause in high-income countries.

Common Retinal Diseases

1. Age-Related Macular Degeneration (AMD)

 AMD  affects central vision and accounts for  8.7%  of global blindness cases. Risk factors include:

  • Age over 55
  • Family history
  • Smoking

Early symptoms include blurred central vision and difficulty reading, while advanced stages may cause distorted vision or blind spots in the center of the visual field.

2. Diabetic Retinopathy

 Diabetic retinopathy  is the  leading cause of blindness among working-age adults in the U.S. , resulting from retinal damage due to high blood sugar. Symptoms include:

  • Blurry vision
  • Floaters
  • Vision loss

3. Retinal Tears

 Retinal tears  occur when the vitreous shrinks and pulls away from the retina, leading to:

  • Sudden floaters
  • Sudden flashes of light

4. Retinal Detachment

 Retinal detachment  is a serious condition requiring urgent medical attention. It is more common in individuals with high myopia or diabetes. Symptoms include:

  • Black spots in vision
  • Sudden flashes of light
  • Darkened or shadowed vision

5. Macular Holes

 Macular holes  mainly affect people aged 60-80, with women being more susceptible. Symptoms include:

  • Blurry vision
  • Distorted vision (straight lines appearing wavy)
  • Loss of central vision

6. Retinoblastoma

 Retinoblastoma  is a rare childhood eye cancer, with 90% of cases occurring in children under 5 years old. Around 40% of cases are inherited. Symptoms include:

  • Bulging eyes
  • Abnormal white reflection in the pupil (leukocoria)

Genetic Retinal Diseases

1. Retinitis Pigmentosa (RP)

 RP  affects 1 in 5000 people worldwide, leading to:

  • Night blindness
  • Peripheral vision loss
  • Central vision impairment

2. Stargardt Disease

 Stargardt disease  affects 1-5 in 10,000 people, causing gradual central vision loss.

3. Best Disease

 Best disease  is caused by mutations in the BEST1 gene, leading to central vision loss.

Symptoms of Retinal Diseases

Treatment Options for Retinal Diseases

1. Injection Therapy

2. Surgical Treatments

Conclusion

Retinal diseases can cause significant vision impairment, but early diagnosis and treatment can improve outcomes. If you experience blurry vision, flashes of light, or black spots in your vision, seek medical attention promptly for the best treatment options.

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